| Named By: | Often credited as Joseph Leidy, Laizer and Parieu named the type species in 1838 |
| Time Period: | Late Eocene to Early Miocene, 42-15.9 Ma |
| Location: | Species known from North America, Asia, Africa and Europe |
| Size: | Largest species (H. gigas) just over 3 meters long and about 110 centimetres high at the shoulder. Smallest species (H. microdon) much smaller at around forty to fifty centimetres long |
| Diet: | Carnivore |
| Fossil(s): | Multiple remains, although usually of only partially preserved individuals |
| Classification: | | Chordata | Mammalia | Creodonta | Hyaenodontidae | |
| Also known as: | | Alloeodectes | Neohyaenodon | Pseudopterodon | |
Hyaenodon ("hyena-tooth") is the type genus of Hyaenodontidae, a group of extinct carnivorous fossil mammals from Eurasia, North America and Africa, with species existing temporally from the Eocene until the middle Miocene, existing for approximately 26.1 million years.
The various species of Hyaenodon competed with each other and with other hyaenodont genera (including Sinopa, Dissopsalis and Hyainailurus), and played important roles as predators in ecological communities as late as the Miocene in Africa and Asia. Species of Hyaenodon have been shown to have successfully preyed on other large carnivores of their time, including a Nimravid ("false sabertooth cat"), Dinictis by analysis of tooth puncture marks on a fossil Dinictis skull in North Dakota.