| Named By: | Fabrini in 1890 |
| Time Period: | Early Pliocene to Late Pleistocene, 4-0.012 Ma [1] |
| Location: | Across Eurasia, Africa, North America, also present in South America (specifically Venezuela) |
| Size: | 1.1 meters high at the shoulder |
| Diet: | Carnivore |
| Fossil(s): | Multiple specimens |
| Classification: | | Chordata | Mammalia | Felidae | Machairodontinae | Machairodontini | |
| Also known as: | | Dinobastis | Ischyrosmilus | |
Homotherium is an extinct genus of machairodontine saber-toothed cats, often termed scimitar-toothed cats, that inhabited North America, South America, Eurasia, and Africa during the Pliocene and Pleistocene epochs (4 mya - 12,000 years ago), existing for approximately 4 million years.
It first became extinct in Africa some 1.5 million years ago. In Eurasia it survived until about 30,000 years ago. In South America it is only known from a few remains in the northern region (Venezuela), from the mid-Pleistocene. The most recent European remains of Homotherium date to 28,000 years BP.