| Named By: | Joseph Liedy in 1853 |
| Time Period: | 42-16.3 Ma Middle Eocene-Early Miocene |
| Location: | Canada, USA |
| Size: | Up to 1.5 meters long, but exact size depends upon the species with some being smaller |
| Diet: | Carnivore |
| Fossil(s): | Multiple specimens |
| Classification: | | Chordata | Mammalia | Carnivora | Caniformia | Amphicyonidae | Daphoeninae | |
| Also known as: | | Daphoenus demilo | Pericyon | Proamphicyon nebrascensis | Protemnocyon hartshornianus | |
Daphoenus is an extinct genus of caniform carnivoran mammal of the family Amphicyonidae ("bear dogs") of the suborder Caniformia. Daphoenus inhabited North America from the Early Eocene subepoch to the Early Miocene subepoch 42--16.3 Mya, existing for approximately 25.7 million years.