| Named By: | M. MacDougall & R. R. Reisz in 2014 |
| Time Period: | Early Permian, Kungurian |
| Location: | USA, Oklahoma - Garber Formation |
| Size: | Unavailable |
| Diet: | Herbivore |
| Fossil(s): | Partial skull and post cranial remains |
| Classification: | | Chordata | Parareptilia | Procolophonomorpha | Nyctiphruretidae | |
Abyssomedon (meaning "Guardian of the Abyss") is an extinct genus of a nyctiphruretid parareptile known from the late Early Permian (Kungurian age) Garber Formation of Comanche County, Oklahoma, south-central United States. It contains a single species, Abyssomedon williamsi, which represents the third known nyctiphruretid species, the oldest species of the family and the first to be discovered in North America.